Post-Genome Informatics

By Minoru Kanehisa

Book Overview

The genome projects have now entered a rapid production phase with complete genome sequences and complete gene catalogues already available for a number of organisms and an increasing number expected shortly. In addition the new DNA and protein chip technologies can produce functional data about genes such as gene expression profiles at a rapid rate. There is therefore a large and ever increasing amount of data about genes and molecules. However there is still a huge gap between information at the molecular level and information at the level of integrated biological systems. It is this gap that is addressed in Post-genome Informatics. Post-genome informatics is the analysis of biological functions in terms of the network of interacting molecules and genes with the aim of understanding how a biological system is organized from its individual building blocks. As well as containing a comprehensive survey of the database and computational technologies relevant to molecular sequence analysis, Post-genome Informatics will provide the reader with a conceptual framework and practical methods for the representation and computation of molecular networks.

• Format: Paperback
• Language: English
• ISBN: 0198503261
• ISBN13: 9780198503262
• Release Date: March 2000
• Publisher: Oxford University Press, USA
• Length: 160 Pages
• Weight: 0.75 lbs.
• Dimensions: 0.4" x 6.4" x 9.2"

Customer Reviews

A vision of future directions

The previous reviewer is correct that this is not a book on coding or data models. But it is not intended to be. The author has a vision of where bioinformatics needs to go and he articulates this clearly. Most books in the field are blinkered by comparison. Chapter 4 on network analysis of moelecular interactions is a valuable (if general) contribution to the discussion on how computational and systems models can be applied to deepening our understanding of how pathways might actually work, and how these models can be connected to existing data resources.The references are somewhat patchy, or I would have given the book five stars, but still provide some useful leads.