Population and Quantitative Genetics: Evolutionary Forces and Complex Traits

By Ser Choiyu

Master the forces that shape genetic variation-and turn them into confident predictions about complex traits. This comprehensive, classroom-tested guide walks you from Hardy-Weinberg intuition and Wright-Fisher dynamics to modern GWAS, QTL mapping, and causal inference. With 33 tightly organized chapters, crystal-clear explanations, and 500+ exam-style multiple choice questions with fully explained answers, it's the fastest path from theory to mastery.

What you'll learn

How selection, drift, mutation, and migration jointly drive allele-frequency change-and when each dominatesWhy effective population size and inbreeding transform variation, fitness, and inferenceThe logic of linkage disequilibrium, recombination, F-statistics, and demographic footprintsThe full quantitative toolkit: variance components, heritability, GxE, epistasis, breeder's equation, and G-matricesHow to design, power, and interpret QTL studies and GWAS with mixed models, fine-mapping, and polygenic scoresHow to separate signal from artifact: stratification, relatedness, assortative mating, pleiotropy, and measurement errorFrom association to causation: robust thinking with within-family designs and Mendelian randomizationHow to read complex-trait claims critically, reproduce results, and communicate them responsibly

Practice and mastery built in

500+ carefully crafted multiple choice questions with step-by-step answers that teach, not just testEnd-of-chapter summaries, key formulas, and common-pitfall checklists to lock in learning quicklyReal-world case studies spanning human disease, agriculture, and conservation genetics

Why this book stands out

Assumptions-first approach: know when methods work-and when they don'tBalanced intuition and math: derivations you can follow, insights you can useDesigned for self-study, exam prep, and course adoption across genetics, evolution, biostatistics, and bioinformatics

Who it's for

Undergraduates and graduate students aiming for top exam scores and deep understandingInstructors seeking a rigorous, modular text with built-in assessmentResearchers and data scientists entering genomics who need a practical, assumption-aware roadmap

• Format: Paperback
• Language: English
• ISBN: B0FTMMFK7L
• ISBN13: 9798268064704
• Release Date: October 2025
• Publisher: Independently Published
• Length: 386 Pages
• Weight: 1.13 lbs.
• Dimensions: 0.8" x 6.0" x 9.0"