Photopolymerizable Porous Polyorganophosphazenes: Degradable Matrices for Tissue Engineering

By Tamara Bernadette Aigner

Tamara Bernadette Aigner designed a set of biocompatible and biodegradable poly(organophosphazenes). In order to tailor their biological and chemical properties, she further modified these macromolecules by adding functional moieties via thiol-ene chemistry. The author used the same photochemistry for crosslinking to obtain a mechanically stable network. She further altered the degradation rate of the matrix as well as the mechanical properties by adding blending agents and created a porous matrix, which is necessary for cell invasion and communication, by a newly developed photocrosslinking particulate-leaching method. Thus, a modular hybrid system was established which is able to adapt to different microenvironments based upon tissue type.

• Format: Paperback
• Language: English
• ISBN: 3658093196
• ISBN13: 9783658093198
• Release Date: March 2015
• Publisher: Springer Spektrum
• Length: 75 Pages
• Weight: 0.30 lbs.
• Dimensions: 0.2" x 5.8" x 8.3"