Pharmacogenomics in Drug Discovery and Development

Book Overview

Part I. Systems and "Omics" Studies in Pharmacogenomics

1. From Pharmacogenomics and Systems Biology to Personalized Care: A Framework of Systems and Dynamical Medicine

Qing Yan

2. Translational Bioinformatics Approaches for Systems and Dynamical Medicine

Qing Yan

3. Whole Blood Transcriptomic Analysis to Identify Clinical Biomarkers of Drug Response

Grant P. Parnell and David R. Booth

4. Diagnostic Procedures for Paraffin Embedded Tissues Analysis in Pharmacogenomic Studies

Raffaele Palmirotta, Maria Laura De Marchis, Giorgia Ludovici, Patrizia Ferroni, Pasquale Abete, Fiorella Guadagni, and David Della-Morte

5. Approach to Clinical and Genetic Characterization of Statin-Induced Myopathy

QiPing Feng

6. Pharmacogenetics of Membrane Transporters: A Review of Current Approaches

Tristan M. Sissung, Andrew K.L. Goey, Ariel M. Ley, Jonathan D. Strope, and William D. Figg

7. G Protein-Coupled Receptor Accessory Proteins and Signaling: Pharmacogenomic Insights

Miles D. Thompson, David E. C. Cole, Pedro A. Jose, and Peter Chidiac

8. G Protein-Coupled Receptor Mutations and Human Genetic Disease

Miles D. Thompson, Geoffrey N. Hendy, Maire E. Percy, Daniel G. Bichet and David E. C. Cole

9. Pharmacogenetics of the G Protein-Coupled Receptors

Miles D. Thompson, David E. Cole, Valerie Capra, G. Enrico Rovati, and Brinda K. Rana

Part II. Clinical Applications of Pharmacogenomics

10. Pharmacogenomics of Heart Failure

Anastasios Lymperopoulos and Faren French

11. Pharmacogenomics in the Development and Characterization of Atheroprotective Drugs

Efi Valanti, Alexandros Tsompanidis, and Despina Sanoudou

12. Management of Side-Effects in the Personalized Medicine Era: Chemotherapy Induced Peripheral Neuropathy

P. Alberti and G. Cavaletti

13. Pharmacogenomics of Alzheimer's Disease: Novel Therapeutic Strategies for Drug Development

Ram?n Cacabelos, Pablo Cacabelos, Clara Torrellas, Sergio Pi?eiro-Hermida, Mar?a J. Villanueva-Mill?n, Cristina Solveira, Iv?n Tellado, and Juan C. Carril

14. Pharmacogenetics of Antipsychotic Treatment in Schizophrenia

Jennie G. Pouget and Daniel J. M?ller

15. Pharmacogenetics of Addiction Therapy

David A. Nielsen, Ellen M. Nielsen, Teja Dasari, and Catherine J. Spellicy

16. Pharmacogenetics in Rheumatoid Arthritis

Deepali Sen, Jisna R Paul, and Prabha Ranganathan

17. The Pharmacogenomics of Osteoporotic Fractures

Jos? A. Riancho and Flor P?rez-Campo

18. Pharmacogenomics and Pharmacoepigenomics in Pediatric Medicine

Barkur S. Shastry

19. Pharmacogenomics in Children

Michael Rieder

• Format: Paperback
• Language: English
• ISBN: 1493947583
• ISBN13: 9781493947584
• Release Date: September 2016
• Publisher: Humana
• Length: 715 Pages
• Weight: 2.75 lbs.
• Dimensions: 1.5" x 7.0" x 10.0"