Pharmacogenomics in Drug Discovery and Development

By Qing Yan

Book Overview

1. Target Discovery for Drug Development Using Mendelian Randomization

Daniel S. Evans

2. Human Leukocyte Antigen (HLA) Testing in Pharmacogenomics

Ann M. Moyer and Manish J. Gandhi

3. Pharmacogenomics in Targeted Therapy and Supportive Care Therapies for Cancer

Zahra Talebi, Alex Sparreboom, and Susan I. Colace

4. Pharmacogenomics in Cytotoxic Chemotherapy of Cancer

Zahra Talebi, Alex Sparreboom, and Susan I. Colace

5. Management of Side Effects in the Personalized Medicine Era: Chemotherapy-Induced Peripheral Neuropathy

Eleonora Pozzi and Paola Alberti

6. The Yin-Yang Dynamics in Cancer Pharmacogenomics and Personalized Medicine

Qing Yan

7. Design of Personalized Neoantigen RNA Vaccines Against Cancer Based on Next Generation Sequencing Data

Bego?a Alburquerque-Gonz?lez, Mar?a Dolores L?pez-Abell?n, Gin?s Luengo-Gil, Silvia Montoro-Garc?a, and Pablo Conesa-Zamora

8. COVID-19 Pharmacotherapy: Drug Development, Repurposing of Drugs, and the Role of Pharmacogenomics

Rebecca Bock, Mariana Babayeva, and Zvi G. Loewy

9. Pharmacogenomics Informs Cardiovascular Pharmacotherapy

Mariana Babayeva, Brigitte Azzi, and Zvi G. Loewy

10. Pharmacogenomic Screening of Patient-Specific hiPSC-Derived Cardiomyocyte Drug Candidates Using High-Throughput Calcium Imaging

Malorie Blancard, K. Ashley Fetterman, and Paul W. Burridge

11. The Yin-Yang Dynamics in Cardiovascular Pharmacogenomics and Personalized Medicine

Qing Yan

12. GTPgS Assay for Measuring Agonist-Induced Desensitization of Two Human Polymorphic Alpha2B-Adrenoceptor Variants

Jordana I. Borges, Alexandra M. Carbone, Natalie Cora, Anastasiya Sizova, and Anastasios Lymperopoulos

13. Pharmacogenomics of Alzheimer's Disease: Novel Strategies for Drug Utilization and Development

Ram?n Cacabelos, Vinogran Naidoo, Olaia Mart?nez-Iglesias, Lola Corzo, Natalia Cacabelos, Roc?o Pego, and Juan C. Carril

14. Pharmacogenetics of Antipsychotic Treatment in Schizophrenia

Samar S.M. Elsheikh, Daniel J. M?ller, and Jennie G. Pouget

15. The Pharmacogenetic Impact on the Pharmacokinetics of ADHD Medications

Jacob T. Brown

16. Pharmacogenetics of Addiction Therapy

David P. Graham, Mark J. Harding, and David A. Nielsen

17. Pharmacogenomics of Opioid Treatment for Pain Management

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• Format: Hardcover
• Language: English
• ISBN: 1071625721
• ISBN13: 9781071625729
• Release Date: September 2022
• Publisher: Humana
• Length: 616 Pages
• Weight: 2.88 lbs.
• Dimensions: 1.4" x 7.0" x 10.0"