Pet Chemistry: The Driving Force in Molecular Imaging

By P.A. Schubiger

Book Overview

Molecular Imaging with PET - Open Questions?.- Fluorine-18 Labeling Methods: Features and Possibilities of Basic Reactions.- Fluorine-18 Labeling of Small Molecules: The Use of 18F-Labeled Aryl Fluorides Derived from No-Carrier-Added [18F]Fluoride as Labeling Precursors.- Fluorine-18 Labeling of Peptides and Proteins.- [18F]Fluoropyridines: From Conventional Radiotracers to the Labeling of Macromolecules Such as Proteins and Oligonucleotides.- Production of Non-standard PET Radionuclides and the Application of Radiopharmaceuticals Labeled with these Nuclides.- Carbon-11 Labeling Chemistry Based upon [11C]Methyl Iodide.- 68Ga-PET Radiopharmacy: A Generator-Based Alternative to 18F-Radiopharmacy.- Microwaving in F-18 Chemistry: Quirks and Tweaks.- Micro-reactors for PET Tracer Labeling.- Synthesis Modules and Automation in F-18 Labeling.- Pharmacological Prerequisites for PET Ligands and Practical Issues in Preclinical PET Research.- Positron Emission Tomography Imaging as a Key Enabling Technology in Drug Development.

• Format: Paperback
• Language: English
• ISBN: 3642421644
• ISBN13: 9783642421648
• Release Date: November 2014
• Publisher: Springer
• Length: 345 Pages
• Weight: 1.11 lbs.
• Dimensions: 0.8" x 6.1" x 9.2"