Pathogenesis of Systemic Lupus Erythematosus: Insights from Translational Research

1. Advances in translational science to identify new therapies for systemic lupus erythematosus. Alberta Hoi and Fabien Vincent.2. Hallmark of systemic lupus erythematosus: Role of B Cell Hyperactivity. Fabien B Vincent, William A Figgett and Margaret L Hibbs.3. B cell targeted therapies in systemic lupus erythematosus. Fabien B Vincent1, William A Figgett and Margaret L Hibbs.4. Type I Interferons and the perpetuation of a loss of tolerance. Kathryn Connelly and Alberta Hoi.5. Therapeutic Modulation of the Interferon Pathway in Systemic Lupus Erythematosus. Shereen Oon.6. The concept of co-stimulatory blockade in SLE. Alberta Hoi.7. Cytokines: their role in amplifying SLE pathogenesis. Bonnia Liu and Alberta Hoi.8. Intracellular targets in SLE. Alberta Hoi.9. Regulatory T cells in SLE. Rachel Cheong and Joshua Ooi.10. Balancing strategies: GC and GILZ Axis. Champa Nataraja, Wendy Zhu, Wendy Dankers and Sarah A. Jones and Alberta Hoi.

• Format: Hardcover
• Language: English
• ISBN: 3030851605
• ISBN13: 9783030851606
• Release Date: November 2021
• Publisher: Springer
• Length: 178 Pages
• Weight: 1.26 lbs.
• Dimensions: 0.5" x 7.0" x 10.0"