Oxidative Stress and Redox Signalling in Parkinson's Disease
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Parkinson's disease is the second most common neurodegenerative disorder affecting millions of people worldwide. In order to find neuroprotective strategies, the mechanisms of the disease need to be understood, and there have been links made between oxidative damage and Parkinson's disease. This book provides a thorough review of the latest research developments regarding the mechanisms by which oxidative stress and redox signalling mediate Parkinson's disease. It is designed to cover basic knowledge regarding oxidative stress and redox signalling, Parkinson's disease, and neurodegeneration, while also exploring in detail the latest advancement in the research field. Topics covered will include dopamine metabolism, metal homeostasis and DNA-damage. The text will also discuss the current advance in the identification of potential biomarkers for diagnosis and disease progression and the future of antioxidant based therapeutics. Written by recognised experts in the field this book will be a great source of information for postgraduate students and academics, clinicians, toxicologists and risk assessment groups.
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