Ovulation Biomarkers in Saliva

By: Saibaba Ganesan

This book explores how saliva can be used as a simple, non-invasive tool to detect ovulation in humans. Saliva contains many important biomolecules, especially proteins, that reflect changes in the body during the menstrual cycle. In this study, the physical, chemical, and ultrastructural properties of saliva were examined across different phases of the cycle, revealing clear variations. Notably, this is the first report to highlight ultrastructural differences in saliva during ovulation. Using advanced proteomic techniques, the study identified significant changes in protein expression, with over 530 proteins detected during the ovulation phase compared to fewer in other phases. Key proteins such as Cystatin-S, prolactin-inducible protein, and carbonic anhydrase 6 were found to be highly expressed during ovulation. Among these, Cystatin-S was validated as a promising biomarker. The findings suggest that saliva-based ovulation detection could support fertility treatments and natural family planning. This research opens the door to developing easy, stress-free biosensors for accurate ovulation prediction.

• Format: Paperback
• Language: English
• ISBN: 6209845665
• ISBN13: 9786209845666
• Release Date: April 2026
• Publisher: LAP Lambert Academic Publishing
• Length: 140 Pages
• Weight: 0.44 lbs.
• Dimensions: 9.0" x 0.3" x 6.0"