Orexin and Sleep: Molecular, Functional and Clinical Aspects

Book Overview

History of Orexin Research.- The Hypocretin Story.- Input and output systems of orexin neurons.- Physiological roles of orexin receptors on sleep/wakefulness regulation.- Orexin receptor functions in the ascending arousal system (Folder name - Leonard).- Elucidation of neuronal circuitry involved in the regulation of sleep/wakefulness using optogenetics (Folder name - Yamanaka).- Modulation of thalamocortical pathways by orexins.- Orexins, Alcohol and Sleep Homeostasis.- Orexin induced modulation of REM sleep and its loss associated patho-physiological changes are mediated through locus coeruleus.- Role of orexin on sleep: interactions with other neurotransmitter systems.

• Format: Paperback
• Language: English
• ISBN: 3319352202
• ISBN13: 9783319352206
• Release Date: August 2016
• Publisher: Springer
• Length: 410 Pages
• Weight: 1.31 lbs.
• Dimensions: 0.9" x 6.1" x 9.2"