Oncolytic Viruses: Methods and Protocols

By David H. Kirn

Book Overview

1. Oncolytic Herpes Simplex Virus Engineering and Preparation

Pankaj K. Agarwalla and Manish K. Aghi

2. Construction of Capsid-modified Adenoviruses by Recombination in Yeast and Purification by Iodixanol-gradient

Marta Gim?nez-Alejandre, Alena Gros, and Ram?n Alemany

3. Construction of Targeted and Armed Oncolytic Adenoviruses

Konstantin Doronin and Dmitry M. Shayakhmetov

4. Syrian Hamster Tumor Model to Study Oncolytic Ad5 Based Vectors

Debanjan Dhar, Karoly Toth, and William S.M. Wold

5. Adenoviral Gene Expression and Replication in Human Tumor Explant Models

Gunnel Halld?n

6. Imaging Luciferase-expressing Viruses

Michael A. Barry, Shannon May, and Eric A. Weaver

7. In vivo Positron Emission Tomography Imaging using the Sodium Iodide Symporter as a Reporter Gene

Lucile Tran, Nad?ge Dartial, Cecilia Hindorf, and Georges Vassaux

8. Maintaining and Loading Neural Stem Cells for Delivery of Oncolytic Adenovirus to Brain Tumors

Atique U. Ahmed, Ilya I. Ulasov, Ronald W. Mercer, and Maciej S. Lesniak

9. Targeting Brain Tumor Stem Cells with Oncolytic Adenoviruses

Marta M. Alonso, Hong Jiang, Candelaria Gomez-Manzano, and Juan Fueyo

10. Propagation, Purification and In vivo Testing of Oncolytic Vesicular Stomatitis Virus Strains

Jean-Simon Diallo, Markus V?h?-Koskela, Fabrice Le Boeuf, and John Bell

11. Oncolytic Measles Virus Retargeting by Ligand Display

Pavlos Msaouel, Ianko D. Iankov, Cory Allen, Stephen J. Russell, Evanthia Galanis

12. Exploring Host Factors that Impact Reovirus Replication, Dissemination, and Reovirus-induced Cell Death in Cancer versus Normal Cells in Culture

Maya Shmulevitz and Patrick W. K. Lee

13. Analysis of Three Properties of Newcastle Disease Virus for Fighting Cancer: Tumor Selective Replication, Antitumor Cytotoxicity and Immunostimulation

Philippe Fournier, Huijie Bian, J?zsef Szeber?nyi, and Volker Schirrmacher

14. Next Generation Oncolytic Vaccinia Vectors

Steve H. Thorne

15. Evaluation of Innate Immune Signaling Pathways in Transformed Cells

Joshua F. Heiber and Glen N. Barber

• Format: Hardcover
• Language: English
• ISBN: 1617793396
• ISBN13: 9781617793394
• Release Date: September 2011
• Publisher: Humana
• Length: 241 Pages
• Weight: 1.44 lbs.
• Dimensions: 0.6" x 7.0" x 10.0"