Oncogene-Induced Senescence: Methods and Protocols

Book Overview

This book offers in a single volume a unique collection of the state-of the-art experimental procedures utilized for the induction, detection, and modeling of this complex cellular program of oncogene-induced senescence. The book encompasses protocols for studying this multi-step program in human specimens and a variety of experimental models including cultured mammalian cells, laboratory mice, and Drosophila melanogaster, as well as offering a description of high throughput approaches. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Oncogene-Induced Senescence: Methods and Protocols represents a valuable asset for a wide audience of medical oncologists and researchers in the fields of oncology, molecular and cellular biology, biochemistry, and animal development.

• Format: Paperback
• Language: English
• ISBN: 1493982672
• ISBN13: 9781493982677
• Release Date: June 2018
• Publisher: Humana
• Length: 220 Pages
• Weight: 0.91 lbs.
• Dimensions: 0.5" x 7.0" x 10.0"