This book examines Octavia E. Butler's Lilith's Brood series to focus on the revolutionary ways she influenced science fiction through challenging treatments of issues including ecological devastation; biological sex; gender, race, sex, and sexualities; biology and identity; and utopian and dystopian themes. By balancing careful, thorough analysis of the trilogy with important biocritical and historical information, Pitts contextualizes the series both within Butler's writing career and the socio-historical milieu in which she wrote. Chapters evidence why Lilith's Brood matters to science fiction studies as a radical challenge to the genre and the culture within which it was produced, as well as why it is similarly deserving of careful consideration by scholars, readers, and fans.