Introduction: Why study Nucleic Acids in vacuo?.- Transferring Nucleic Acids to the Gas Phase.- Structure of Nucleic Acids in the Gas Phase.- Interactions between Nucleic Acid Ions and Electrons and Photons.- Gas-phase Spectroscopy of Nucleic Acids.- Fragmentation Reactions of Nucleic Acid Ions in the Gas Phase.- Characterization of Ribonucleic Acids and their Modifications by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.- Quantification of DNA Damage using Mass Spectrometry Techniques.- Ligand Binding to Nucleic Acids.- MS-based Approaches for Nucleic Acid Structural Determination.
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