Section 1. Pharmacology and Mechanisms Chapter 1. Chemistry, Pharmacodynamics, and Pharmacokinetics of NSAIDsSara Calatayud and Juan Vicente Esplugues Chapter 2. Principles, Mechanisms of Action, and Future Prospects of Anti-Inflammatory DrugsBibiana Rius and Joan Cl?ria Section 2. Clinical Effects and Drug Safety Chapter 3. Efficacy of NSAIDs in the Treatment of Rheumatic DiseasesMarc C. Hochberg and Lee S. Simon Chapter 4. Adverse Effects of NSAIDs in the Gastrointestinal Tract: Risk Factors of Gastrointestinal Toxicity with NSAIDsSunny H. Wong and Francis K.L. Chan Chapter 5. Adverse Effects of NSAIDs on the Cardiovascular SystemCarmelo Scarpignato and Corrado Blandizzi Chapter 6. Safe Prescription of NSAIDs in Clinical PracticeMohammad Yaghoobi and Richard H. Hunt Section 3. Aspirin Chapter 7. NSAIDS and Aspirin: Recent Advances and Implications for Clinical ManagementKarsten Schr?r and Michael Voelker Chapter 8. Non-Prescription Analgesic Anti-inflammatory Drugs: Efficacy and SafetyDenis M. McCarthy Chapter 9. Low-Dose Aspirin in the Cardiovascular SystemRuben Casado-Arroyo, Angel Lanas, and Pedro Brugada Chapter 10. Adverse Effects of Low-Dose Aspirin in the Gastrointestinal TractKatsunori Iijima Chapter 11. Aspirin in the Treatment and Prevention of Cardiovascular Disease: Need for Individual Clinical JudgmentsAngel Lanas and Charles H. Hennekens Section 4. NSAIDS and Aspirin in Cancer Prevention Chapter 12. Molecular and Experimental Basis for COX-Inhibition in CancerAnnalisa Bruno, Melania Dovizio, and Paola Patrignani Chapter 13. Clinical Effects of NSAIDs and Coxibs in Colon Cancer PreventionElena Piazuelo and Angel Lanas Chapter 14. Aspirin and the Prevention of Colorectal Cancer Paul J. Lochhead and Andrew T. Chan Chapter 15. A Rational Approach for the Use of NSAIDs and/or Aspirin in Cancer Prevention in the Near Future: "Balancing Risk and Benefits"Elizabeth Half, Ahmad Fokra, and Nadir Arber
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