Non Viral Gene Therapy: Gene Design and Delivery Vol 2

By Merita Rumano and Diana Avetyan

Principles of Non-Viral Gene Therapy: Provide a comprehensive introduction to the principles of non-viral gene therapy, including the advantages and limitations compared to viral-based methods. Discuss the basic concepts of gene therapy, gene transfer, and the fundamental goals of therapeutic gene delivery.

Gene Design Strategies: Explore various strategies for designing therapeutic genes, including gene editing techniques (e.g., CRISPR/Cas9), synthetic gene constructs, and expression vectors. Discuss the considerations for optimizing gene design for therapeutic efficacy, stability, and expression.

Non-Viral Delivery Systems: Examine the different non-viral delivery systems used for gene transfer, including physical methods (e.g., electroporation, microinjection), chemical methods (e.g., liposomes, nanoparticles), and biological methods (e.g., cell-penetrating peptides). Discuss the mechanisms, advantages, and challenges associated with each delivery system.

Applications and Therapeutic Outcomes: Discuss the applications of non-viral gene therapy in various therapeutic areas, such as cancer treatment, genetic disorders, and regenerative medicine. Provide case studies and examples of successful non-viral gene therapy applications and their outcomes in clinical and preclinical settings.

• Format: Hardcover
• Language: English
• ISBN: B0F8C4885M
• ISBN13: 9781787154346
• Release Date: January 2025
• Publisher: Kruger Brentt Publisher Uk. Ltd.
• Length: 322 Pages
• Weight: 2.28 lbs.
• Dimensions: 0.8" x 8.5" x 11.0"