Part I: Psychiatry of Demyelinating Diseases.- The Spectrum of Demyelinating Inflammatory Diseases of the Central Nervous System.- Depression and Multiple Sclerosis: Clinical Aspects, Epidemiology and Management.- Depression and Multiple Sclerosis: Imaging, Mechanisms.- Anxiety and Multiple Sclerosis.- Multiple Sclerosis and Bipolar Disorders.- Psychiatric Co-morbidity.- Psychiatric Presentation of Brain Inflammation.- Drug Management of Psychiatric Co-morbidity in Multiple Sclerosis.- Part II: Psychology.- Psychology of Multiple Sclerosis.- Coping and Multiple Sclerosis.- Fatigue.- Psychological and Behavioral Therapies in Multiple Sclerosis.- Part III: Cognitive Perspective.- Introduction to Social Cognition.- Psychopathology of Alexithymia and Multiple Sclerosis.- Social Cognition and Multiple Sclerosis.- Cognitive Impairment in Multiple Sclerosis.- Neuropsychiatry of Neuromyelitis Optica.- Dementia in Multiple Sclerosis.- Depression, Anxiety and Cognitive Functioning in Multiple Sclerosis.