Neuronal Signal Transduction and Alzheimer's Disease

By C. O'Neill and O'Neill C Ed

Brings together key researchers from diverse biochemical areas to focus on signal-transduction dysfunction in Alzheimer's disease. Specific topics include modulation of beta-amyloid production and fibrillization, genetic dissection of primary neurodegenerative diseases, neurofibrillary tangles and tau phosphorylation, and apolipoprotein E gene and Alzheimer's disease. Other subjects include regulation of gene expression by muscarinic acetylcholine receptors, and modeling Alzheimer's disease in multiple transgenic mice. Although specifically focused on Alzheimer's disease, material presented here has many parallels in other neurodegenerative disorders and will be of interest to those studying neuronal cell development and function in health and disease.

• Format: Hardcover
• Language: English
• ISBN: 1855781336
• ISBN13: 9781855781337
• Release Date: February 2001
• Publisher: Portland Press, London
• Length: 213 Pages