Neurodegenerative Diseases: Pathology, Mechanisms, and Potential Therapeutic Targets

Book Overview

Part 1: Major Neurodegenerative Conditions .- Alzheimer's Disease - Insights from Genetic Mouse Models and Current Advances in Human IPSC-Derived Neurons.- Clinical Aspects of Alzheimer's Disease.- Parkinson's Disease: Basic Pathomechanisms and a Clinical Overview.- Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets.- The Complexity of Clinical Huntington's Disease: Developments in Molecular Genetics, Neuropathology and Neuroimaging Biomarkers.- Motoneurone Disease - Basic Science.- Motoneurone Disease - Clinical.- Multiple Sclerosis - Basic and Clinical.- Part 2: Other Neurological Conditions .- Schizophrenia-Basic and Clinical.- Stroke - Basic and Clinical.- Epileptic Encephalopathies as Neurodegenerative Disorders.- Neurodegeneration and Pathology in Epilepsy-Clinical and Basic Perspectives.- Prion Disease - Basic and Clinical.- Leukodystrophies - Basic and Clinical.- Traumatic Brain Injury as a Trigger of Neurodegeneration.- Part 3: Key Background and Key Technologies.- Cell Death Mechanisms of Neurodegeneration.- Neuroglia: Functional Paralysis and Reactivity in Alzheimer's Disease and Other Neurodegenerative Pathologies.- Advances in Neuroimaging for Neurodegenerative Disease.- Gene Linkage and Systems Biology.- Biomarkers in Neurodegenerative Diseases.

• Format: Hardcover
• Language: English
• ISBN: 3319571915
• ISBN13: 9783319571911
• Release Date: July 2017
• Publisher: Springer
• Length: 542 Pages
• Weight: 2.10 lbs.
• Dimensions: 1.2" x 6.1" x 9.2"