This is the first comprehensive review of all aspects of nociceptor function, including the structure of nociceptor endings, neurochemistry, and evolutionary considerations. It deals with the functional properties of nociceptors innervating different organs and the biophysical mechanisms underpinning the transduction process in nociceptors. Sections cover the modification of nociceptor function by nerve injury and regeneration, as well as its physiopathology. This is an essential reference for researchers in neuroscience and pharmacology, and clinicians working in pain management.
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