Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers: Multidisciplinary Management

Introduction.- State-of-the art and ongoing developments.- Clinical cases debate: neoadjuvant checkpoint inhibition vs standard chemotherapy.- Slideshow of tumor samples before and after checkpoint inhibition.- Ongoing trials and clinical trials endpoints debate: the role of pathological response as a surrogate of survival endpoints.- State-of-the-art and future role of molecular biomarkers for patient selection.- Background of immunotherapy trials in prostate cancer.- Clinical case debate: immunotherapy vs alternative therapies in the neoadjuvant and adjuvant setting of localized, high-risk prostate cancer.- Cytoreductive nephrectomy in the era of targeted therapy and immunotherapy.- Clinical cases debate: Neoadjuvant vs adjuvant immunotherapy in localized RCC.- Benchmark of surgical safety results.- What the scientific data tell us about predictive biomarkers of immunotherapy efficacy across the GU malignancies.- Clinical cases debate: biomarker-driven patient selection vs unselective perioperative strategies.

• Format: Paperback
• Language: English
• ISBN: 3030805484
• ISBN13: 9783030805487
• Release Date: January 2023
• Publisher: Springer
• Length: 315 Pages
• Weight: 1.04 lbs.
• Dimensions: 0.7" x 6.1" x 9.2"