This volume reviews molecular biology techniques in relation to how th ey have been used to elucidate brain function at the molecular level. Techniques for handling DNA, RNA, proteins, and simple electrophysiolo gy are included. The book examines the major classes of molecules that are of interest to neurobiologists, such as voltage dependent ion cha nnels, all the major receptor superfamilies and second messenger syste ms, transporters, growth, and neurotrophic factors. This is done by re viewing exciting problems in neuroscience such as mechanisms of transm itter release, channel gating, brain plasticity, development, and diff erentiation. In addition, the book provides wherever possible, links b etween basic neuroscience, brain disease and molecular approaches to t herapy.
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