Modulation of Protein Stability in Cancer Therapy

By Kathleen Sakamoto

Book Overview

Ubiquitin Ligases and Cancer.- The 26S Proteasome as a Therapeutic Target in Cancer: Beyond Protease Inhibitors?.- Targeting HAUSP: Killing Two Birds with One Stone.- Modulation of Protein Stability: Targeting the VHL Pathway.- Interrelationship of the Fanconi Anemia/BRCA Pathway.- Targeting the Sumoylation Pathway.- Proteasome Inhibitors.- Targeting Deubiquitinating Enzymes.- Proteolysis Targeting Chimeric Molecules.

• Format: Paperback
• Language: English
• ISBN: 1441924019
• ISBN13: 9781441924018
• Release Date: October 2010
• Publisher: Springer
• Length: 165 Pages
• Weight: 0.56 lbs.
• Dimensions: 0.4" x 6.1" x 9.2"