"The Last Frontier" sees Miso and Kili journeying to Alaska, where they meet the Eskimo Cats and experience the wonders of ice hole fishing and sled bunny racing. Their adventure reaches a climax when Miso and Kili are separated after a meeting with a pack of Alaskan Huskies, only to be reunited with the help of the Huskies, revealing the coexistence of the cats and dogs in the wild.