Microwave assisted synthesis of pyrazolo-phthalazine compounds

By Nileshkumar Dhirubhai Vala

This book surrounded with the microwave assisted synthesis of some new 3-substituted-pyrazol-1H-pyrazolo 1,2-b]phthalazine-5,10-dione derivatives and investigation of their antimicrobial activity. The one-pot three-component, microwave assisted condensation reaction of 3-substituted-1H-pyrazole-4-carbaldehyde 1a-d with cyano-active methelene 2a-d and 2,3-dihydro-1,4-phthalazinedione 5 proceeded effortlessly in ethanol in presence of triethyl amine (TEA) as a catalyst to give corresponding 3-substituted-pyrazol-1H-pyrazolo 1,2-b]phthalazine-5,10-dione derivatives in good to excellent yields. So, it is admirable to express brief about synthetic and biological significance of the phthalazine.

• Format: Paperback
• Language: English
• ISBN: 6200300291
• ISBN13: 9786200300294
• Release Date: August 2019
• Publisher: LAP Lambert Academic Publishing
• Length: 56 Pages
• Weight: 0.21 lbs.
• Dimensions: 0.1" x 6.0" x 9.0"