Microwave-assisted CAN promoted synthesis of poly-substituted pyridine

By Nileshkumar Dhirubhai Vala

This book compiles with the microwave-assisted synthesis, characterization and in vitro antimicrobial evaluation of 2,4,6-trisubstituted pyridine derivatives catalyzed by ceric ammonium nitrate (CAN), also the effect of halogen substitution on antimicrobial activities. This synthetic study involves one pot cyclo-condensation reaction of 3-substituted-1H-pyrazole-4-carbaldehyde 1a-d and various substituted acetophenone 7a-d under microwave irradiation catalyzed by ceric ammonium nitrate (CAN) to gives 2,4,6-trisubstituted pyridine derivatives 8a-p. So, it is worthy to narrate brief introduction regarding CAN and synthetic and biological consequence of the 2,4,6-trisubstituted pyridine (polysubstituted pyridine) derivatives.

• Format: Paperback
• Language: English
• ISBN: 6200306605
• ISBN13: 9786200306609
• Release Date: September 2019
• Publisher: LAP Lambert Academic Publishing
• Length: 60 Pages
• Weight: 0.22 lbs.
• Dimensions: 0.1" x 6.0" x 9.0"