Peptide Synthesis and Applications

By John Howl

Book Overview

Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools and biological probes, and the design and application of fluorescent substrate-based peptides that can be used to determine the selectivity and activity of peptidases. A practical guide to the identification of proteins using mass spectrometric analyses of peptide mixtures is also included.

• Format: Hardcover
• Language: English
• ISBN: 1588293173
• ISBN13: 9781588293176
• Release Date: February 2005
• Publisher: Humana
• Length: 262 Pages
• Weight: 1.35 lbs.
• Dimensions: 0.8" x 14.5" x 9.2"