Method Development and Validation of Zopiclone by RP-HPLC.

By Rahul Khaire

A simple, sensitive, rapid and selective isocratic reversed phase High Performance Liquid Chromatographic (HPLC) method has been developed for Zopiclone from bulk drug using a mobile phase consisting mixture of Acetonitrile: Buffer (pH 2.8) (80:20v/v) Composition of buffer: (0.272gm in 200ml HPLC water and pH adjusted to 2.8 using ortho Phosphoric acid) at the flow rate of 1.0 mL/min. A Cosmosil C18 (250 cm x 4.6 mm, 5 μm) column was used as stationary phase.

• Format: Paperback
• Language: English
• ISBN: 6202563710
• ISBN13: 9786202563710
• Release Date: May 2020
• Publisher: LAP Lambert Academic Publishing
• Length: 120 Pages
• Weight: 0.41 lbs.
• Dimensions: 0.3" x 6.0" x 9.0"