Metals and Genetics

By Bibudhendra Sarkar

Book Overview

Eulogy for Karen Wetterhahn: As an Introduction to the Session "Genetic Response to Environmental Exposure to Metals" for the Second International Symposium on Metals and Genetics.- Genetic Response to Environmental Exposure to Metals and Metal Transport.- 1. Metalloregulation of Soft Metal Resistance Pumps.- 2. Clastogenic Effects and Influence of Inorganic Arsenic on DNA-Repair in Mammalian Systems.- 3. Groundwater Arsenic Contamination and Sufferings of People in West Bengal, India and Bangladesh: Status Report Up to March, 1998.- 4. The Nature and Extent of Arsenic-Affected Drinking Water in Bangladesh.- 5. Chromium Biomonitoring: Achievements, Problems, and Future Challenges.- 6. Chelate Sensor Method for Mercury.- 7. Copper Transport and Ceruloplasmin during Lactation and Pregnancy.- Metal Carcinogenesis and Metal Caused DNA Damage.- 8. CAP43: A New Gene Induced by a Rise in Free Intracellular Ca2+ following Ni2+ Exposure.- 9. Zinc and Metallothionein in Mammalian Cell Cycle Regulation.- 10. Effect of Metal Compounds on the Function of Zinc Finger Proteins Involved in DNARepair.- 11. Chromium(III) as a Male Preconception Carcinogen in Mice.- 12. DNA Cleavage vs. Cross-Linking Using Nickel Peptides: Mechanistic Aspects.- 13. Copper-Dependent DNA Scission 197.- 14. Modulation of Glucocorticoid Signaling and Leukocyte Activation by Transition Metals.- Metals and Neurodegenerative Diseases.- 15. Reactions of Copper-Zinc Superoxide Dismutases with Hydrogen Peroxide: Possible Involvement in Familial Amyotrophic Lateral Sclerosis.- 16. Yeast Mitochondrial Iron Metabolism and the Pathophysiology of Friedreich' Ataxia.- 17. Getting Copper into Mitochondria.- Genetics and Biochemistry of Metal-Related Diseases.- 18. The Copper-Transporting ATPase Defective in Wilson Disease.- 19. Towards the Characterization of the Wilson Disease Copper ATPase Metal Binding Domain.- 20. Molecular Genetics of Menkes Disease.- 21. Mutational Analysis of the Copper ATPase Affected in Menkes Disease.- 22. Clinicopathological and Molecular Genetic Features of Hereditary Ceruloplasmin Deficiency (Aceruloplasminemia).- 23. Copper Related Liver Disease in Young Children.- Metals and Gene Regulation.- 24. Regulation of Zinc Homeostasis in Yeast by the ZAP1 Transcriptional Activator.- 25. Embryonic Liver Degeneration and Increased Sensitivity Towards Heavy Metal and H2O2 in Mice Lacking the Metal-Responsive Transcription Factor MTF-1.- 26. The Transport and Intracellular Trafficking of Metal Ions in Yeast.- 27. Mechanisms of Copper Chaperone Proteins.- 28. Transcriptional Regulation of the Gene Encoding Mouse Metallothionein-3.- Contributors.

• Format: Hardcover
• Language: English
• ISBN: 0306461013
• ISBN13: 9780306461019
• Release Date: May 1999
• Publisher: Springer
• Length: 412 Pages
• Weight: 1.88 lbs.
• Dimensions: 0.9" x 6.7" x 9.6"