Mesenchymal Stem Cell Development

By K R San

The capacity for self-renewal and the capacity for multi-lineage development are two traits that define stem cells. Together, these two characteristics are frequently referred to as stemness. hMSCs, or human mesenchymal stem cells, are no different. Because of their capacity for trilineage differentiation and their immunomodulatory properties, hMSCs have shown great promise in the fields of tissue engineering and regenerative medicine.
They may be used to treat conditions like diabetes, heart disease, wound healing, graft vs host disease, and a number of autoimmune illnesses. Adult tissues that can be used to produce hMSCs include bone marrow, adipose tissue, and tooth pulp. They also don't raise any ethical concerns because they are taken from consenting persons.
The limited availability of hMSCs in tissues is one of the major obstacles to achieving the full therapeutic potential of these cells, as the authors of this book investigate.
Additionally, as donors age, less viable MSCs are available for their tissue aspirations, making the situation even more pressing.
This book, look into how the stiffness of the substrate-the surface to which cells adhere-affects the control of MSC migration, lineage differentiation, replicative senescence, and cell proliferation.

• Format: Paperback
• Language: English
• ISBN: B0CWJW9PNG
• ISBN13: 9798869201355
• Release Date: February 2024
• Publisher: Self Publishing
• Length: 172 Pages
• Weight: 0.53 lbs.
• Dimensions: 9.0" x 0.4" x 6.0"