Marfan Syndrome: A Primer for Clinicians and Scientists

By Peter N. Robinson

Book Overview

Marfan Syndrome is a hereditary disorder of connective tissue which primarily affects the cardiovascular, skeletal, and ocular systems. Remarkable progress in the field has been made in both clinical and basic-science research since the discovery of the gene for fibrillin-1 (FBN1) in 1991, mutations in which cause the Marfan syndrome. Marfan Syndrome: A Primer for Clinicians and Scientists presents a comprehensive overview of clinical aspects of Marfan syndrome, FBN1 mutation analysis, the biology of fibrillin and fibrillin-containing microfibrils, and the molecular pathogenesis of the Marfan syndrome. The authors are prominent and active researchers in clinical and basic-science research on Marfan syndrome and fibrillin.

• Format: Hardcover
• Language: English
• ISBN: 030648238X
• ISBN13: 9780306482380
• Release Date: November 2004
• Publisher: Springer
• Length: 218 Pages
• Weight: 1.10 lbs.
• Dimensions: 0.6" x 6.1" x 9.2"