Critical Infrastructures.- Modelling dependencies between critical infrastructures.- Critical Infrastructures disruption scenario analyses via simulation.- Physical simulators of critical infrastructures.- Phenomenological simulators of critical infrastructures.- Federated simulations.- Cyber and physical threats modelling.- Verification and validation.- Design of DSS for supporting preparedness to and management of anomalous situations in complex scenarios.- The use of What-if analysis to improve the management of critical situations.- Model coupling with OpenMI introduction of basic concepts.