After getting cursed by a young witch, short-tempered teen KJ Hendrickson is taken to the only orphanage in Chicago that cares for children with magical ailments: Malison's Home for the Cursed. KJ makes friends with a jinxed, optimistic girl named Laura Sanderson. KJ gets accustomed to staying at Malison's. However, both of them soon realize a mysterious secret behind the kindly Caregiver and the orphanage owner, Mr. Malison.