Listeria monocytogenes is an important food-borne pathogen that has the capacity to cause severe infections, such as gastroenteritis, septicemia, abortion and meningitis in humans and animals. The alternative sigma factors (σB, σC, σH, & σL) are responsible for regulating transcription of several Listeria monocytogenes virulence factors and stress response genes, including hemolysin gene (hly) that contribute to establishment of intracellular infection.
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