Discovery of leptin and elucidation of leptin gene expression.- Leptin receptors and mechanism of action.- Leptin interaction with brain orexigenic and anorexigenic pathways.- Measurement of circulating leptin and soluble leptin receptors.- Physiological and hormonal factors that influence leptin production.- Leptin, obesity and leptin resistance.- Leptin and intermediary metabolism: Focus on glucoregulation and lipid metabolism.- Leptin in acute...