1 Introduction.- 2 Space and Ground-Based Infrastructures.- 2.1 Characteristics of the Space Environment.- 2.2 Space Infrastructure.- 2.3 Non-orbital weightless research platforms.- 2.4 Ground-based facilities and space simulators.- 3 Areas of research.- 3.1 Physical sciences.- 3.2 Life sciences.- 4 ULISSE access to data.- 4.1 Data description.- 4.2 Identification of information: the ULISSE knowledge base.- 4.3 ULISSE: data access services.