Interaction of Nanomaterials with the Immune System

Overview of immune response to nanomaterials caused by either inhalation, oral, or dermal exposure.- Engineered nanomaterials: synthesis, characterization, uses and exposure.- Impact of nanomaterials on barrier function.- Complement activation and inflammation.- Macrophage function and phagocytosis.- Mast cells.- Impact on dendritic cell - lymphocyte function.- Impact on host pathogen response and microbiome.- Allergy/autoimmunity.- Pre-existing allergic or bacterial-induced lung disease.- Nanomaterial effects on viral infection.- Immunotoxicity and carcinogenesis.- In vivo animal models (nude mice, transgenic models).- In vitro cell culture models.- In silico computational modeling.- Summary of mechanisms of immune modulation.

• Format: Hardcover
• Language: English
• ISBN: 3030339610
• ISBN13: 9783030339616
• Release Date: January 2020
• Publisher: Springer
• Length: 223 Pages
• Weight: 1.12 lbs.
• Dimensions: 0.6" x 6.1" x 9.2"