1 Introduction.- 2 Theoretical Frameworks: A Spatial Perspective on Innovation and the Genesis of Regional Growth.- 3 Geographical Accessibility and Human Capital Accumulation.- 4 The Role of Underlying Socio-Economic Conditions.- 5 Knowledge Flows and Their Spatial Extent.- 6 Innovation in an Integrated Framework: A Europe-United States Comparative Analysis.- 7 What Can We Learn from the "Integrated Approach" to Regional Development? The Impact of EU Infrastructure Investment.- 8 EU Development Policies and the Socio-Economic Disadvantage of European Regions.- 9 Conclusions.- References.- Appendices
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