Inflammation-Associated Depression: Evidence, Mechanisms and Implications

Book Overview

Section 1: Evidence for inflammation-associated depression.- Evidence for inflammation-associated depression.- Role of inflammation in the development of neuropsychiatric symptom domains.- Inflammation-associated comorbidity.- Section 2: Mechanisms of inflammation-associated depression.- Mechanisms of inflammation-associated depression Immune-to-brain communication pathways and cytokines.- Immune-to-brain communication pathways.- Mechanisms of inflammation-associated depression.- Role of the kynurenine metabolism pathway.- Depression in autoimmune diseases.- Stress-induced microglia activation.- Inflammation effects on brain glutamate.- The role of dopamine.- Brain structures implicated in inflammation-associated depression.- Role of kynurenine metabolism pathway.- Suicidality. Section 3: Clinical implications of inflammation-associated depression.- The promise and limitations of anti-inflammatory agents.- Are non-steroidal anti-inflammatory drugs.- Does diet matter?- Role of neuroimunological factors.

• Format: Paperback
• Language: English
• ISBN: 3319845810
• ISBN13: 9783319845814
• Release Date: July 2018
• Publisher: Springer
• Length: 356 Pages
• Weight: 1.13 lbs.
• Dimensions: 0.8" x 6.1" x 9.2"