Improving the Therapeutic Ratio in Head and Neck Cancer: Volume 6

Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic. The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance. This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites.

• Format: Hardcover
• Language: English
• ISBN: 012817868X
• ISBN13: 9780128178683
• Release Date: October 2019
• Publisher: Academic Press
• Length: 376 Pages
• Weight: 2.00 lbs.
• Dimensions: 0.9" x 7.6" x 9.3"