Immunological Mechanisms and Therapies in Brain Injuries and Stroke

Book Overview

Old dogmas, surprising complexities, and novel therapeutic targets.- The critical roles of immune cells in acute brain injuries.- Vascular Inflammation in Ischemic Stroke: Adhesion Receptors Controlling Leukocyte-Endothelial Interactions.- Immune Cell-Derived Free Radicals in Acute Brain Injury.- The complement cascade in acute brain injury.- Matrix Metalloproteinases as an Inflammatory Mediator in the Neurovascular Unit.- Toll-Like Receptors in Ischemic Stroke and other Acute Brain Injuries.- Ion Transporters in Microglial Function: New therapeutic targets for neuroinflammation in ischemic stroke?.- Inflammation After Acute Brain Injuries Affects the Developing Brain Differently than the Adult Brain.- Systemic Immune Responses after Experimental Stroke.- Infectious Burden and Risk of Stroke.- Inflammatory Biomarkers in Patients with Acute Brain Injuries.- In vivo Imaging of Neuroinflammation in Acute Brain Injury.- Inflammation as a therapeutic target after subarachnoid hemorrhage: advances and challenges.- Minocycline, a Tetracycline Derivative, as a Potential Protective Agent for Acute Stroke.- Tolerization to Brain and Vascular Antigens: Targeting Autoimmunity after Acute Brain Injuries and Preventing Stroke.- The Role of PPARg in Stroke.- CD36: an inflammatory mediator in acute brain injury.- Cool Down the Inflammation: Hypothermia as a Therapeutic Strategy for Acute Brain Injuries.- Index.

• Format: Paperback
• Language: English
• ISBN: 1493944959
• ISBN13: 9781493944958
• Release Date: August 2016
• Publisher: Springer
• Length: 386 Pages
• Weight: 1.22 lbs.
• Dimensions: 0.8" x 6.1" x 9.2"