Hydrophilic Matrix Tablets for Oral Controlled Release

By Peter Timmins

Book Overview

.- 1 Hydrophilic Matrix Dosage Forms: Definitions, General Attributes and the Evolution of Clinical Utilization

.- 2 Design and Evaluation of Hydroxypropyl Methylcellulose Matrix Tablets for Oral Controlled Release: a Historical Perspective

.- 3 An Industrial Perspective on Hydrophilic Matrix Tablets based on Hyproxypropyl Methylcellulose (Hypromellose)

.- 4 Natural Polysaccharides in Hydrophilic Matrices

.- 5 Applications of Polyethylene Oxide (POLYOX) in Hydrophilic Matrices

.- 6 A Formulation Development Perspective on Critical Interactions Affecting the Performance of Hydrophilic Matrix Tablets

.- 7 In vitro Physical and Imaging Techniques to Evaluate Drug Release Mechanisms from Hydrophilic Matrix Tablets

.- 8 Physiologically-Based Pharmacokinetic Modelling in the Development and Evaluation of Hydrophilic Matrix Tablets

.- 9 Approaches to Rapid In Vivo Optimization of Hydrophilic Matrix Tablets

.- 10 Extrusion: an Enabling Technology for Controlled Release Hydrophilic Matrix Systems

.- 11 Microenvironmental pH Control and Mixed Polymer Approaches to Optimize Drug Delivery with Hydrophilic Matrix Tablets

.- 12 Evolving Biopharmaceutics Perspectives for Hydrophilic Matrix Tablets: Dosage Form-Food Interactions and Dosage Form Gastrointestinal Tract Interactions.

• Format: Paperback
• Language: English
• ISBN: 149394827X
• ISBN13: 9781493948277
• Release Date: September 2016
• Publisher: Springer
• Length: 326 Pages
• Weight: 1.04 lbs.
• Dimensions: 0.7" x 6.1" x 9.2"