Homologation Reactions, 2 Volumes: Reagents, Applications, and Mechanisms

By Vittorio Pace

Provides a unique summary of homologation strategies in organic synthesis

Homologation Reactions presents different concepts underpinning the use of homologating reagents as well as their applications in organic synthesis. It covers in-depth discussions on the rationales governing this kind of transformations with a strong emphasis on mechanistic elements modulating critical aspects (e.g. selectivity) of the processes. In addition, this two-volume work features: Metal carbenoids, ylides, and diazo reagents Homologating agents working under nucleophilic, electrophilic, and radical regime Homologations realized on boron-containing or carbon-centered linchpins Use of highly sensitive fluorinated homologating agents Progressive homologations and the concept of assembly line synthesis Homologation processes followed by rearrangement cascades Construction of cyclic motifs and ring-expansion Homologation reactions with carbon monoxide and carbon dioxide New and/or challenging directions to expect in the future

Written by an international team of leaders in the field, the book is a useful guide for designing effective transformations by using homologation reactions. It is a must-read for every synthetic chemist in academia and industry!

• Format: Hardcover
• Language: English
• ISBN: 3527348158
• ISBN13: 9783527348152
• Release Date: May 2023
• Publisher: Wiley-Vch
• Length: 960 Pages