(1) The long period of analysis: Unique is the approach to present several substance biographies which analyze the handling of various hazardous chemicals in different countries during the course of two centuries. (2) The comparative approach applied to several different substances, and several countries. (3) The broad introduction which traces the concept of poison and that of hazardous chemicals from Antiquity until our time gives a valuable overview over the evolving toxicological knowledge and the reaction of the society to that knowledge in different countries. (4) Putting the history of toxic substances into the larger context of hazardous substances.
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