Gene Vaccines

Book Overview

The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles...

• Format: Hardcover
• Language: English
• ISBN: 3709104386
• ISBN13: 9783709104385
• Release Date: September 2011
• Publisher: Springer
• Length: 330 Pages
• Weight: 1.45 lbs.
• Dimensions: 0.7" x 6.3" x 9.4"