Gametogenesis: Primordial germ cells; Mitosis and Meiosis; Maturation of the female gamete; Imprinting and epigenetic regulation; Fertilization; Oocyte activation.- Early embryo development: Syngamy and spindle formation; Cleavage, compaction and blastulation; Cell commitment and Waddington model of epigenetic restriction. Asymmetric imprinting; Establishment of the body axis.- Stem cells and gametogenesis: Oocyte competence and potency; Oocyte as a source of uniparental pluripotent cells; Spindles of uniparental origin in mammals; Stem cells as a source of oocytes.
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