Development of the CNS are extremely sensitive to heat stress (40 1 C); this may lead, in turn, to some harmful effect on the histological structures and neurons formation of the rat newborns. Also, after stopping the exposure to high temperature still has partially delayed the degree of neurogenesis and enzyme activities. ● Egress of free radicals from inside cell to outside through the membrane due to exposure of the rat newborns to the high temperature, and these release reflect the pathological changes in the different regions of central nervous system (CNS) and the reverse is true. ● Heat stress caused a disturbance in the secretion and turnover of the monoamine contents in the CNS and in the synthesis, release of the cholinesterase activity and the cholinergic functions.
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