Exon Skipping and Inclusion Therapies: Methods and Protocols

Book Overview

This book presents a comprehensive collection of detailed state-of-the-art exon skipping and splices modulation protocols. Chapters detail 14 genetic diseases, AON-mediated therapies, and CRISPR/Cas9-mediated gene editing therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Exon Skipping and Inclusion Therapies: Methods and Protocols aims to help researchers initiate the development of next-generation therapies.

• Format: Hardcover
• Language: English
• ISBN: 1493986503
• ISBN13: 9781493986507
• Release Date: September 2018
• Publisher: Humana
• Length: 569 Pages
• Weight: 2.71 lbs.
• Dimensions: 1.3" x 7.0" x 10.0"