Epigenetics in Organ Specific Disorders: Volume 34

**Selected for Doody's Core Titles(R) 2024 in Clinical Genetics**

Epigenetics in Organ Specific Disorders, a new volume in the Translational Epigenetics series, provides a foundational overview and nuanced analysis of epigenetic gene regulation distinct to each organ type and organ specific disorders, fully elucidating the epigenetics pathways that promote and regulate disease. After a brief introduction, chapter authors compare epigenetic regulations across normal and disease conditions in different organ tissues, exploring similarities and contrasts. The role of epigenetic mechanisms in stem cells, cell-matrix interactions and cell proliferation, cell migration, cellular apoptosis, necrosis, pyknosis, tumor suppression, and immune responses across different organ types are examined in-depth.

Organ specific epigenetic mechanisms and biomarkers of early use in developing drugs, which can selectively target the organ of interest, are also explored to enable new precision therapies.

• Format: Paperback
• Language: English
• ISBN: 012823931X
• ISBN13: 9780128239315
• Release Date: December 2022
• Publisher: Academic Press
• Length: 666 Pages