Contents: Some Aspects of Present and Future High Resolution Electron Microscopy and Image Processing (H Hashimoto); Imaging Defects by TEM and SEM (P B Hirsch); Electron Microscopy and Science (E Zeitler); Ultracytochemical Observation of Lysosomal Movements (K Ogawa et al.); Application of High Resolution Electron Microscopy in Molecular and Atomic-Level Investigation of Biological and Clinical Materials (Y S Lee); Ultrastructure of Rat Mast Cell Cytoskeleton and Degranulation (E Y Chi); The Current Status of the Cytoskeleton (D Rayns); Three-Dimensional Imaging of Complex Cell Structures by High Resolution, Low Voltage SEM (H Ris & S S Lim); Advances in Protein Electron Crystallography (W Chiu et al.); Electron Tomography of Biological Macromolecules (W Baumeister et al.); Leydig Cell - A Normal Cell Model of Cellular Autophagy (X M Tang et al.); Ultrastructural Analysis of Regenerating Explants (K Pihakaski-Maunsbach et al.); Ultrastructural Study of Spermatogenic Cells of the Gastropod Pila Luzonica (B C Ramos); Various Shapes of HIV-1 Particles and Their Significance (M Nakai); and other papers;